Polymorphism in Pharmaceutical Drugs by Supercritical CO2 Processing: Clarifying the Role of the Antisolvent Effect and Atomization Enhancement
CRYSTAL GROWTH \& DESIGN, 16, 6222-6229
11 2016
Miguel Rodrigues , Joao M. Tiago , Andreia Duarte , Vitor Geraldes , Henrique A. Matos , Edmundo Azevedo
Insight into the Mechanisms of Cocrystallization of Pharmaceuticals in Supercritical Solvents
CRYSTAL GROWTH \& DESIGN, 15, 3175-3181
7 2015
Luis Padrela , Miguel Rodrigues , Joao Tiago , Sitaram P. Velaga , Henrique A. Matos , Edmundo Azevedo
New Thermoresistant Polymorph from CO2 Recrystallization of Minocycline Hydrochloride
PHARMACEUTICAL RESEARCH, 31, 3136-3149
11 2014
Miguel Rodrigues , Joao M. Tiago , Luis Padrela , Henrique A. Matos , Teresa G. Nunes , Lidia Pinheiro , Antonio J. Almeida , Edmundo Azevedo
Tuning physicochemical properties of theophylline by cocrystallization using the supercritical fluid enhanced atomization technique
JOURNAL OF SUPERCRITICAL FLUIDS, 86, 129-136
2 2014
Luis Padrela , Miguel Rodrigues , Joao Tiago , Sitaram P. Velaga , Henrique A. Matos , Edmundo Azevedo
Single-Step Co-Crystallization and Lipid Dispersion by Supercritical Enhanced Atomization
CRYSTAL GROWTH \& DESIGN, 13, 4940-4947
11 2013
Joao M. Tiago , Luis Padrela , Miguel Rodrigues , Henrique A. Matos , Antonio J. Almeida , Edmundo Azevedo
The Importance of Heat Flow Direction for Reproducible and Homogeneous Freezing of Bulk Protein Solutions
BIOTECHNOLOGY PROGRESS, 29, 1212-1221
9 2013
Miguel Rodrigues , Gustavo Balzan , Monica Rosa , Diana Gomes , Edmundo Azevedo , Satish K. Singh , Henrique A. Matos , Vitor Geraldes
Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 82, 392-400
10 2012
Miguel Rodrigues , Lara Figueiredo , Luis Padrela , Ana Cadete , Joao Tiago , Henrique A. Matos , Edmundo Azevedo , Helena F. Florindo , Lidia Goncalves , Antonio J. Almeida
Powder X-ray diffraction method for the quantification of cocrystals in the crystallization mixture
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 38, 923-929
8 2012
Luis Padrela , Edmundo Azevedo , Sitaram P. Velaga
Theophylline polymorphs by atomization of supercritical antisolvent induced suspensions
JOURNAL OF SUPERCRITICAL FLUIDS, 58, 303-312
9 2011
Miguel Rodrigues , Luis Padrela , Vitor Geraldes , Jose Santos , Henrique A. Matos , Edmundo Azevedo
Screening for pharmaceutical cocrystals using the supercritical fluid enhanced atomization process
JOURNAL OF SUPERCRITICAL FLUIDS, 53, 156-164
6 2010
Luis Padrela , Miguel Rodrigues , Sitaram P. Velaga , Anabela Fernandes , Henrique A. Matos , Edmundo Azevedo
Formation of indomethacin-saccharin cocrystals using supercritical fluid technology
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 38, 9-17
8 2009
Luis Padrela , Miguel Rodrigues , Sitaram P. Velaga , Henrique A. Matos , Edmundo Azevedo
Calculation of Solid-Liquid-Gas Equilibrium for Binary Systems Containing CO2
INDUSTRIAL \& ENGINEERING CHEMISTRY RESEARCH, 48, 4579-4586
5 2009
Jindui Hong , Hui Chen , Jun Li , Henrique A. Matos , Edmundo Azevedo
Anti-solvent effect in the production of lysozyme nanoparticles by supercritical fluid-assisted atomization processes
JOURNAL OF SUPERCRITICAL FLUIDS, 48, 253-260
4 2009
Miguel Rodrigues , Jun Li , Luis Padrela , Antonio J. Almeida , Henrique A. Matos , Edmundo Azevedo
Using N-2- or CO2-assisted atomization process to produce polyethylene glycol microparticles
CHEMICAL ENGINEERING RESEARCH \& DESIGN, 85, 987-995
7 2007
L. Zhao , J. Li , Miguel Rodrigues , Henrique A. Matos , Edmundo Azevedo
Vapor-liquid equilibria and volume expansion of the tetrahydrofuran/CO2 system: Application to a SAS-atomization process
JOURNAL OF SUPERCRITICAL FLUIDS, 41, 343-351
7 2007
Jun Li , Miguel Rodrigues , Alexandre Paiva , Henrique A. Matos , Edmundo Azevedo
Efficiency of water removal from water/ethanol mixtures using supercritical carbon dioxide
BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING, 23, 205-212
4 2006
MA Rodrigues , J Li , AJ Almeida , HA MATOS , Edmundo Azevedo
Binary solid-liquid-gas equilibrium of the tripalmitin/CO2 and ubiquinone/CO2 systems
FLUID PHASE EQUILIBRIA, 241, 196-204
3 2006
J Li , Miguel Rodrigues , Alexandre Paiva , HA MATOS , Edmundo Azevedo
VLE of carbon dioxide/ethanol/water: Applications to volume expansion evaluation and water removal efficiency
INDUSTRIAL \& ENGINEERING CHEMISTRY RESEARCH, 44, 6751-6759
8 2005
J Li , Miguel Rodrigues , HA MATOS , Edmundo Azevedo
Modeling of the PGSS process by crystallization and atomization
AICHE JOURNAL, 51, 2343-2357
8 2005
J Li , Miguel Rodrigues , Alexandre Paiva , HA MATOS , Edmundo Azevedo
High pressure phase equilibrium for delta-tocopherol + CO2
FLUID PHASE EQUILIBRIA, 216, 53-57
2 2004
P Pereira , B Coto , C Menduina , Edmundo Azevedo , MN da Ponte